Spaniard cruises to 6-0, 6-3, 6-0 victory over American wild card at Roland Garros
The 31-year-old certainly needed to familiarise himself with such surroundings having not played in the main draw in Paris since 2010.
Later that year Ginepri, a former top-15 player, broke his elbow after falling off his bicycle and he has not been back in the top 100 since.
Nadal was therefore the last man he would have wanted to be drawn against, and the Spaniard, looking to become the first main to win five successive French Open titles, was typically ruthless.
Ginepri enjoyed a decent spell early in the second set but could make no headway on Nadal's serve and found his own under constant pressure.
Nadal is likely to find things tougher in the second round, where 20-year-old rising star Dominic Thiem could well be his opponent.